Global transcriptional response of Methylorubrum extorquens to formaldehyde stress expands the role of EfgA and is distinct from antibiotic translational inhibition.

*Bazurto, JV, *Riazi S, D’Alton S, Deatherage DE, Bruger EL, Barrick JE, Marx CJ. Global transcriptional response of Methylorubrum extorquens to formaldehyde stress expands the role of EfgA and is distinct from antibiotic translational inhibition. Microorganisms. 9:347 (2021). doi.org/10.3390/microorganisms9020347
Read More Global transcriptional response of Methylorubrum extorquens to formaldehyde stress expands the role of EfgA and is distinct from antibiotic translational inhibition.

Formaldehyde-responsive proteins, TtmR and EfgA, reveal a tradeoff between formaldehyde resistance and efficient transition to methylotrophy in Methylorubrum extorquens.

Bazurto JV, Bruger EL, Lee JA, Lambert LB, Marx CJ. Formaldehyde-responsive proteins, TtmR and EfgA, reveal a tradeoff between formaldehyde resistance and efficient transition to methylotrophy in Methylorubrum extorquens. Journal of Bacteriology. 203:e00589-20 (2021). doi.org10.1128/JB.00589-20
Read More Formaldehyde-responsive proteins, TtmR and EfgA, reveal a tradeoff between formaldehyde resistance and efficient transition to methylotrophy in Methylorubrum extorquens.

EfgA is a conserved formaldehyde sensor that leads to bacterial growth arrest in response to elevated formaldehyde.

Bazurto JV, Nayak DD, Ticak T, Davlieva M, Lee JA, Hellenbrand CN, Lambert LB, Benski OJ, Quates CJ, Johnson JL, Patel, JS, Ytreberg FM, Shamoo Y, Marx CJ. EfgA is a conserved formaldehyde sensor that leads to bacterial growth arrest in response to elevated formaldehyde. PLOS Biology. 19:e3001208 (2021). [pdf] doi.org/10.1371/journal.pbio.3001208
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Methylothon

Ceci Martinez-Gomez, Jessica Lee, and I have begun a new outreach effort as part of our NSF Dimensions of Biodiversity project (). We call this the Methylothon: a multi-way competition between natural isolates of Methylobacterium collected by high school students, so far having been run…
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