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Large-effect beneficial synonymous mutations mediate rapid and parallel adaptation in a bacterium.
Agashe D, Sane M, Phalnikar K, Diwan GD, Habibullah A, Martinez-Gomez NC, Sahasrabuddhe V, Polachek W, Wang J, Chubiz LM, Marx CJ. Large-effect beneficial synonymous…
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Selection maintains apparently degenerate metabolic pathways due to tradeoffs in using methylamine for carbon versus nitrogen.
Nayak DD, Agashe D, Lee M-C, Marx CJ. Selection maintains apparently degenerate metabolic pathways due to tradeoffs in using methylamine for carbon versus nitrogen.…
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Transfer of a catabolic pathway for chloromethane in Methylobacterium strains highlights different limitations for growth with chloromethane or with dichloromethane.
Michener JK, Vuilleumier S, Bringel F, Marx CJ. Transfer of a catabolic pathway for chloromethane in Methylobacterium strains highlights different limitations for growth with chloromethane or with dichloromethane.…
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Adding biotic complexity alters the metabolic benefits of mutualism.
Harcombe WR, Betts A, Shapiro JW, Marx CJ. Adding biotic complexity alters the metabolic benefits of mutualism. Evolution. 70:1871-1881 (2016). [pdf]
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Parallel mutations result in a wide range of cooperation and community consequences in a two-species bacterial consortium.
Douglas SM, Chubiz LM, Harcombe WR, Ytreberg FM, Marx CJ. Parallel mutations result in a wide range of cooperation and community consequences in a two-species bacterial…
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Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment.
*Bradley AS, *Swanson PK, Muller EEL, Bringel F, Carroll SM, Pearson A, Vuilleumier S, Marx CJ. Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment. PLOS One. 12:e0173323…
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A transdisciplinary approach to the initial validation of a single cell protein as an alternative protein source for use in aquafeeds.
Tlusty MF, Rhyne AL, Szczebak JT, Bourque BD, Bowen JL, Burr G, Marx CJ, Feinberg L. A transdisciplinary approach to the initial validation of a…
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The E. coli molecular phenotype under different growth conditions.
Caglar MU, Houser JR, Barnhardt CS, Boutz DR, Carroll SM, Dasgupta A, Lenoir WF, Smith BL, Sridhara V, Sydykova DK, Vander Wood D, Marx CJ, Marcotte…
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dentification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation.
Douglas SM, Chubiz LM, Harcombe WR, Marx CJ. Identification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation. PLOS…
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Growth tradeoffs accompany the emergence of glycolytic metabolism in Shewanella oneidensis MR-1.
Chubiz LM, Marx CJ. Growth tradeoffs accompany the emergence of glycolytic metabolism in Shewanella oneidensis MR-1. Journal of Bacteriology. 199:e00827-16 (2017). [pdf]
